Ross Alexander David Bathgate,Mohammed Akhter Hossain,Chrishan Surendran Samuel,John Desmond Wade,Geoffrey W Tregear
申请号：
US12740450
公开号：
US09056922B2
申请日:
2008.10.30
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Provided herein are modified relaxin polypeptides wherein the B chain comprises the core amino acid sequence CGR-XXX-R-XX-I/V-XX-CG (SEQ ID NO:1), where X is any amino acid. Also provided are modified relaxin polypeptides comprising at least an A and a B chain, wherein the A and B chains are derived from different naturally occurring relaxins and wherein the B chain comprises the core amino acid sequence CGR-XXX-R-XX-I/V-XX-CG (SEQ ID NO:1), where X is any amino acid.
