The invention relates to an immunomagnetic nanocomposite fabricated via hydrophobic interaction. The immunomagnetic nanocomposite comprises a core, a shell, and an outer layer. The core is encapsulated in the shell formed by a complex, wherein the complex is composed of fucoidan, oxidized dextran, and a plurality of superparamagnetic iron oxide nanoparticles. The outer layer contains at least one antibody, which is immobilized to outside of the shell to form the outer layer. Thus, the immunomagnetic nanocomposite can be used to prepare anticancer drugs.本發明提供一種免疫磁性組成物，其包含一核心層、一殼層、以及一外層。所述殼層係由一複合物所構成，且所述殼層包覆所述核心層。所述複合物係由褐藻多醣、氧化右旋糖酐及超順磁性氧化鐵奈米粒子經疏水性作用力結合而形成。所述外層包含至少一抗體，且所述抗體嫁接於殼層外構成所述外層。藉此，前述免疫磁性組成物可用於製備抗癌的藥物。
