This invention provides an anti-cancer peptide, use of the peptide and a medical composition containing the same, which comprises lipopolysaccharide-binding peptide LPSBD0 or LPSBD2 and is demonstrated to have anti-cancer activity against breast cancer, liver cancer, lung cancer and colorectal cancer.本發明係提供一種抗癌胜肽、該胜肽之用途以及含有該胜肽之醫藥組成物,其包含有脂多醣結合胜肽LPSBD0或LPSBD2,對於乳癌、肝癌、肺癌以及大腸直腸癌均具有抗癌的活性。