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Novel heterocyclic compound or salt thereof
专利权人:
TAISHO PHARMACEUTICAL CO.; LTD.
发明人:
NOGUCHI, TOSHIYA,野口寿也,野口壽也,USHIYAMA, FUMIHITO,牛山文仁,牛山文仁,HORIKIRI, HIROMASA,堀切裕正,堀切裕正,YAMAMOTO, KEIKO,山本惠子,山本惠子,ONO, NAOYA,小野直哉,小野直哉,TAKAYAMA, TETSUO,高山哲男,高山哲男,KAMIYAMA, TOMOKO,神山朋子,神山朋子
申请号:
TW100118295
公开号:
TW201209056A
申请日:
2011.05.25
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
Disclosed is a medicament having a strong antibacterial activity against Gram-positive bacteria, Gram-negative bacteria, and resistant bacteria. A compound represented by formula [I] or a salt thereof is useful as an antibacterial agent. In formula [I], a bond containing a dotted line and connecting X2 to Y1 represents a single bond or a double bond Z1, Z2, Z3, Z4, Z5, and Z6 each represent a nitrogen atom, formula: CH, or the like X1 represents a C1-4 alkylene group which may be substituted by an oxo group X2 represents a bonding hand or formula: CH Y1 represents a spirocyclic group selected from a group of formulae (II) X3 represents a C1-4 alkylene group, formula: NR10(CH2)m, formula: SOn, or a bonding hand and R7 represents a C3-6 cycloalkyl group, a C3-6 cycloalkenyl group, an aryl group, a monocyclic heterocyclic group, a bicyclic heterocyclic group, or the like.本發明係關於提供一種對革氏陽性菌、革氏陰性菌及耐性菌具有強抗菌活性的藥劑。式[I]式[I]所示化合物或其鹽可作為抗菌劑使用。(式中,含有連結X2與Y1的點線之鍵結表示單鍵或雙鍵,Z1、Z2、Z3、Z4、Z5、Z6表示氮原子或式CH等,X1表示可由側氧基取代之C1-4伸烷基,X2表示鍵結鍵或式CH,Y1表示選自式群(II)的螺環基等,X3表示C1-4伸烷基、式NR10(CH2)m、式SOn或鍵結鍵,R7表示C3-6環烷基、C3-6環烯基、芳基、單環雜環基或二環雜環基等)。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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