A battery replacement system configured to replace battery for an electric vehicle includes a control system, a first self-propelled battery module and a second self-propelled battery module in communication with the control system. The first self-propelled battery module is configured to detach from the electric vehicle upon receiving an appropriate command from the control system, and second self-propelled battery module is configured to be mounted to the electric vehicle upon receiving an appropriate command from the control system. The first self-propelled battery module and the second self-propelled battery module are capable of moving automatically to an predetermined position. An using method of the battery replacement system is also provided.