TSAI, MING SHIUN,蔡明勳,WANG, SUE HONG,王淑红,王淑紅,CHAO, SHIH CHING,赵士庆,趙士慶,YUO, SHIN HWEI,尤新辉,尤新輝,YU, FU HUA,游富华,游富華
申请号：
TW107115088
公开号：
TW201946639A
申请日:
2018.05.03
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
The present invention provides a kind of Cordyceps militaris extract that can be reduced anticancer drug and cause injury of kidney, with and preparation method thereof. First, cordyceps are through plate culture, the culture of liquid strain bacterium, Gu Tai Fermentation ferment culture, obtain fruiting bodies of cordyceps militaris, in addition, fruiting bodies of cordyceps militaris is separated with water hot extraction, then with alcohol, further increase cordycepin content, a Cordyceps militaris extracts composition is obtained, and the extracts composition is carried out with the acute kidney injury animal experiment of anticancer drug initiation, confirming to have reduces the purposes that anticancer drug causes injury of kidney.本發明提供一種能降低抗癌藥物造成腎損傷的蛹蟲草萃取物，以及其製備方法。首先，蛹蟲草菌透過平板培養、液體種菌培養、固態醱酵培養，獲得蛹蟲草子實體，再之，蛹蟲草子實體以熱水萃取，再以酒精分離，進一步提高蟲草素含量，獲得一蛹蟲草萃取組合物，並將該萃取組合物進行以抗癌藥物引發之急性腎損傷動物試驗，確認具有降低抗癌藥物造成腎損傷的用途。
