ANDRÁS DANCSÓ,BALÁZS VOLK,EDE MÁRVÁNYOS,GÀBOR NÉMETH,JÓZSEF BARKÓCZY,LÁSZLÓ PONGÓ,MÓNIKA MEZÖVÁRI,ZOLTÁN VARGA
申请号：
BR112014008733
公开号：
BR112014008733A2
申请日:
2012.10.10
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
abstract the invention relates to erlotinib salts selected from the group consisting of the maleic acid salt. salicylic acid salt. l-mandelic acid alt. adipinic acid salt. 1,5-naphthalene disulfonic acid salt. 1-pyroglutamic acid salt. 1-hydroxy-2-naphthoic acid salt. and mandelic acid salt and amorphous and crystalline forms. hydrates and solvates thereof. the erlotinib salts of the present invention are useful in therapy. particularly for the treatment or prophylaxis of non-small cell lung carcinoma and pancreas rarcinoma. translation of the abstract patent summary: "erlotinib salts". The present invention relates to erlotinib salts selected from the group consisting of maleic acid salt, salicylic acid salt, 1-mandelic acid salt, adipinic acid salt, 1,5-naphthalenic acid salt. disulfonic acid, 1-pyroglutamic acid salt, 1-hydroxy-2-naphthoic acid salt and mandelic acid salt and amorphous and chrysaltine forms, hydrates and solvates thereof. The erlotinib salts of the present invention are useful in therapy, particularly for the treatment or prophylaxis of non-small cell lung carcinoma and pancreatic carcinoma.abstract the invention relates to erlotinib salts selected from the group consisting of the maleic acid salt. salicylic acid salt. l-mandelic acid alt. adipinic acid salt. 1.5-naphthalene-disulfonic acid salt. l-pyroglutamic acid salt. 1-hydroxy-2-naphthoic acid salt. and mandelic acid salt and amorphous and crystalline forms. hydrates and solvates thereof. the erlotinib salts of the present invention are useful in therapy. particularly for the treatment or prophylaxis of non-small cell lung carcinoma and pancreas rarcinoma. tradução do resumo resumo patente de invenção: "sais de erlotinib". a presente invenção refere-se aos sais de erlotinib selecio-nados do grupo consistindo em sal de ácido maleico, sal de ácido sali-cílico, sal de ácido l-mandélico, sal de ácido adipínico, sal de ácido 1,5-naftalênico-dissulfônico, sal de ácido l-piroglutâmico, sal de ácido
