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Salt forms of a xanthine derivative
专利权人:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
发明人:
SIEGER PETER,PFRENGLE WALDEMAR
申请号:
NZ59292409
公开号:
NZ592924A
申请日:
2009.12.22
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed herein are salt forms of 1-[(4 -methyl-quinazolin-2-yl) methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(R)-amino-piperidin-1-yl)-xanthine, a DPP- 4 inhibitor and their use in pharmaceutical compositions useful in the treatment of type 2, diabetes, as well as their production. In specific embodiments the salt is the benzenesulfonic acid, hydrobromic acid, benzoic acid, ethanesulfonic acid, fumaric acid, salicylic acid, p-toluenesulfonic acid, glycolic acid, malonic acid or 2,5-dihydroxybenzoic acid salt.
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