Kenneth W. Foreman,Hanh N. Nguyen,Leslie O. Ofori,Jutta Wanner,Douglas S. Werner
申请号:
US15889638
公开号:
US20190290771A1
申请日:
2018.02.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Described herein are silicon based conjugates capable of delivering one or more payload moieties to a target cell or tissue. Contemplated conjugates may include a silicon-heteroatom core, one or more optional catalytic moieties, a targeting moiety that permits accumulation of the conjugate within a target cell or tissue, one or more payload moieties (e.g., a therapeutic agent or imaging agent), and two or more non-interfering moieties covalently bound to the silicon-heteroatom core.