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Silicon based drug conjugates and methods of using same
专利权人:
发明人:
Kenneth W. Foreman,Hanh N. Nguyen,Leslie O. Ofori,Jutta Wanner,Douglas S. Werner
申请号:
US15477721
公开号:
US09931407B2
申请日:
2017.04.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Described herein are silicon based conjugates capable of delivering one or more payload moieties to a target cell or tissue. Contemplated conjugates may include a silicon-heteroatom core, one or more optional catalytic moieties, a targeting moiety that permits accumulation of the conjugate within a target cell or tissue, one or more payload moieties (e.g., a therapeutic agent or imaging agent), and two or more non-interfering moieties covalently bound to the silicon-heteroatom core.
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