Li Chen,Michael Patrick Dillon,Lichun Feng,Ronald Charles Hawley,Minmin Yang
申请号：
US15383245
公开号：
US09896439B2
申请日:
2016.12.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Compounds of the formula I:or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted pyrazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.
