Li Chen;Michael Patrick Dillon;Ronald Charles Hawley;Minmin Yang;Lichun Feng
发明人:
Li Chen,Michael Patrick Dillon,Lichun Feng,Ronald Charles Hawley,Minmin Yang
申请号：
US12317008
公开号：
US08440673B2
申请日:
2008.12.17
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Compounds of the formula I:or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted pyrazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.
