Yingjie Lai;Li Chen;Michael Patrick Dillon;Minmin Yang;Lichun Feng
发明人:
Li Chen,Lichun Feng,Minmin Yang,Michael Patrick Dillon,Yingjie Lai
申请号：
US13359330
公开号：
US20120122886A1
申请日:
2012.01.26
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compounds of the formula I:or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted thiadiazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.
