GEORGE R. PAINTER,DENNIS C. LIOTTA,DARRYL CLEARY,MERRICK ALMOND,JOSÉ SORIA,MARCOS L. SZNAIDMAN
申请号:
PT10181678
公开号:
PT2322518E
申请日:
1999.08.12
申请国别(地区):
PT
年份:
2015
代理人:
摘要:
Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include efficient methods for the preparation of the 1,3-oxathiolane ring and subsequent condensation of the 1,3-oxathiolane with a pyrimidine or purine base. Using the processes described herein, the compounds can be provided as isolated enantiomers.