Stable antibody formulation

• 收藏
• 分享

专利权人:

アムジエン・インコーポレーテツド

发明人:

マコーリー，アーノルド,レーダー，ダグラス,マツムラ，マサズミ,マコーリー,アーノルド,レーダー,ダグラス,マツムラ,マサズミ

申请号：

JP2009531481

公开号：

JP5631591B2

申请日:

2007.10.05

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The invention provides a formulation including an acetic acid buffer, a glutamic acid buffer or a succinic acid buffer with a pH from about 4.5-7.0, at least one excipient comprising a sugar or a polyol and an effective amount of a therapeutic antibody. The buffer can include a salt of acetate, glutamate or succinate and the sugar or polyol can include glycerol, sucrose, trehalose or sorbitol. The therapeutic antibody can include a human antibody, a humanized antibody, a chimeric antibody, or a functional fragment thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/