PROBLEM TO BE SOLVED: To provide a method of manufacturing a sphingolipid-containing composition which has high safety, no problem in blending and in which a use amount of solvent required for extraction can be minimized.SOLUTION: Provided is a method of manufacturing a sphingolipid-containing composition in which an organic solvent is added to a residue of squeezed juice obtained by squeezing citrus fruit to extract sphingolipid into the organic solvent, a method of manufacturing a sphingolipid-containing composition in which an enzyme is added to a residue of squeezed juice obtained by squeezing citrus fruit to perform enzyme treatment, or a method of manufacturing a sphingolipid-containing composition in which fruit juice obtained by squeezing citrus fruit is subjected to heavy centrifugal separation to collect a sedimentation part.COPYRIGHT: (C)2014,JPO&INPIT【課題】 安全性が高く、配合時の問題もなく、抽出に要する溶媒の使用量も低く抑えることが可能なスフィンゴ脂質含有組成物の製造方法を提供する。【解決手段】 カンキツ類の果実を搾汁して得られる搾汁残さに有機溶剤を添加し、該有機溶媒中にスフィンゴ脂質を抽出することを特徴とするスフィンゴ脂質含有組成物の製造方法、カンキツ類の果実を搾汁して得られる搾汁残さに酵素を添加して酵素処理することを特徴とするスフィンゴ脂質含有組成物の製造方法、又はカンキツ類の果実を搾汁して得られる果汁を、重遠心分離して沈殿部を回収することを特徴とするスフィンゴ脂質含有組成物の製造方法。【選択図】図1