NAKDONGGANG NATIONAL INSTITUTE OF BIOLOGICAL RESOURCES;국립낙동강생물자원관
发明人:
KIM MIN JIN,김민진,KANG CHANG HEE,강창희,JEONG YONG TAE,정용태,KIM CHUL HWAN,김철환,HAN WOONG,한웅,HWANG BUYNG SU,황병수,YU SANG MI,유상미,EOM JUNG HYE,엄정혜,OH YOUNG TAEK,오영택,JEONG SANG CHUL,정상철
申请号：
KR1020180034868
公开号：
KR1020190112915A
申请日:
2018.03.27
申请国别(地区):
KR
年份:
2019
代理人:
摘要：
The present invention discloses a composition for anti-inflammation using a Monochoria korsakowii extract which inhibits NO production in a concentration-dependent manner in a mouse macrophage line (RAW 264.7 cells) stimulated with lipopolysaccharide (LPS), inhibits the production of inflammatory cytokines, TNF-&alpha； and PGE2, and has the inhibitory activity of the expression of COX-2, an inflammation mediator.COPYRIGHT KIPO 2020본 발명은, LPS(lipopolysaccharide)로 자극된 마우스 대식세포주(RAW 264.7 cells)에서 농도 의존적으로 NO 생성을 억제하고 염증성 사이토카인 TNF-α의 생성과 PGE2의 생성을 억제하며, 염증매개인자인 COX-2의 발현을 억제 활성을 가진, 물옥잠 추출물을 이용한 항염증용 조성물을 개시한다.
