The Regents of the University of Colorado, a body corporate;The Johns Hopkins University
发明人:
Martin G. Pomper,Catherine A. Foss,Joshua M. Thurman,V. Michael Holers
申请号:
US15511597
公开号:
US20190240355A9
申请日:
2015.09.15
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The presently disclosed subject matter provides compositions and kits comprising light-emitting versions of the monoclonal antibody to C3d (mAB 3d29) for imaging and methods of use thereof for detecting infectious and inflammatory cells in vivo. The presently disclosed subject matter also provides methods for detecting and/or monitoring a Mycobacterium tuberculosis (M. tuberculosis) infection in a subject, as well as methods of treating a M. tuberculosis infection in a subject.