POURASHRAF, MEHRNAZ,JACQUEMOT, GUILLAUME,CLARIDGE, STEPHEN,BAYRAKDARIAN, MALKEN,JOHNSTONE, SHAWN,ALBERT, JEFFREY S.,GRIFFIN, ANDREW
申请号:
CA2994478
公开号:
CA2994478A1
申请日:
2016.08.12
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
This application relates to substituted benzimidazoles of formula (I), compositions comprising them and their uses in the treatment of diseases and conditions in which inhibition of a bromodomain is indicated. For example, the application relates to substituted benzimidazoles and to their use as bromodomain inhibitors. The present application also relates to the treatment or prevention of proliferative disorders, auto-immune disorders, inflammatory disorders, dermal disorders, and neoplasm, including tumors and/or cancers.