JACQUEMOT, GUILLAUME,BAYRAKDARIAN, MALKEN,JOHNSTONE, SHAWN,ALBERT, JEFFREY S.,GRIFFIN, ANDREW
申请号：
CA2994472
公开号：
CA2994472A1
申请日:
2016.08.11
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
This application relates to aryl-substituted dihydroquinolinones of formula (I), compositions comprising them and their uses in the treatment of diseases and conditions in which inhibition of a bromodomain is indicated. For example, the application relates to aryl-substituted dihydroquinolinones and to their use as bromodomain inhibitors. The present application is also related to the treatment or prevention of proliferative disorders, auto-immune disorders, inflammatory disorders, dermal disorders, and neoplasms, including tumors and/or cancers.
