Guillaume JACQUEMOT,Stephen CLARIDGE,Malken BAYRAKDARIAN,Shawn JOHNSTONE,Jeffrey S. ALBERT,Andrew GRIFFIN
申请号：
US15751789
公开号：
US20200024253A1
申请日:
2016.08.11
申请国别(地区):
US
年份:
2020
代理人:
摘要：
This application relates to N-substituted bicyclic lactams of formula (I), compositions comprising them and their uses in the treatment of diseases and conditions in which inhibition of a bromodomain is indicated. For example, the application relates to the N-substituted bicyclic lactams of formula (I) and to their use as bromodomain inhibitors. The present application is also related to the treatment or prevention of proliferative disorders, auto-immune disorders, inflammatory disorders, dermal disorders, and neoplasms, including tumors and/or cancers.
