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SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS
专利权人:
NEOMED Institute
发明人:
Mehrnaz POURASHRAF,Guillaume JACQUEMOT,Stephen CLARIDGE,Malken BAYRAKDARIAN,Shawn JOHNSTONE,Jeffrey S. ALBERT,Andrew GRIFFIN
申请号:
US15751801
公开号:
US20180237417A1
申请日:
2016.08.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
This application relates to substituted benzimidazoles, compositions comprising them and their uses in the treatment of diseases and conditions in which inhibition of a bromodomain is indicated. For example, the application relates to substituted benzimidazoles and to their use as bromodomain inhibitors. The present application is also related to the treatment or prevention of proliferative disorders, auto-immune disorders, inflammatory disorders, dermal disorders, and neoplasms, including tumors and/or cancers.
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