A cartridge (2) with a fill level detection system (10, 10&prime, 10&Prime), the cartridge comprising a substantially rigid containing wall (4) having a tubular wall portion (12) surrounding a chamber (18) for receiving liquid therein, a plunger or piston (8) mounted inside the chamber and configured to seal one side of the chamber, the plunger or piston being displaceable in the chamber towards an outlet end (14) of the cartridge, characterized in that the fill level detection system comprises a plurality of discrete fixed electrodes (24, 24&prime) positioned along the tubular wall portion in a juxtaposed manner in a direction of displacement D of the plunger or piston (8), and a mobile electrode member (28) fixed to the plunger or piston and displaceable therewith.