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A new technology of oligomeric protein mixed enzyme and copolymer strengthening was obtained.
专利权人:
MSD WELLCOME TRUST HILLEMAN LABORATORIES PVT. LTD.
发明人:
GILL, Davinder,CHHIKARA, Manoj Kumar,RANA, Rakesh,DALAL, Juned,SINGH, Deepti
申请号:
CL2017000844
公开号:
CL2017000844A1
申请日:
2017.04.06
申请国别(地区):
CL
年份:
2017
代理人:
摘要:
<; p >; improved process of conjugaci Bertalanffy to obtain New (Sint ticos oligosac & eacute; of & aacute; Hybrid Sint ticos - & eacute; Protein & iacute; nas (PR).The M & eacute; all of conjugaci Bertalanffy os pr Sint tico is a M & eacute; R & eacute; all & nbsp; ask for acquiring Bertalanffy Conjugates oligosac & aacute; rido prote & iacute; na are highly inmunog & eacute; nicos and provoke responses specific immune & amp; and homogenous & eacute; neas.The oligosac & aacute; rido Sint tico & eacute; comprising of four to eight Repeat units of Bertalanffy consist in their respective Mon & amp; and at least a mere Linker amino terminal Integrated Said polysaccharides & aacute; rido Sint tico & eacute; that mimics a natural polysaccharides obtained & nbsp; Hybrid from Gram negative bacteria such as Neisseria meningitidis serogroups, & nbsp; a, C and W,X and Haemophilus influenzae and Protein & iacute; a Carrier is obtained from Gram positive bacteria such as Clostridium tetani (toxoid Tet & aacute; nico) or corynebaclterium diphtheriae (CRM197) or recombinant versions. The conjugaci Bertalanffy qu & iacute; mica Said oligosac & aacute; rido prote & iacute; na conjugate according to the invention, Bertalanffy, the link is Uncle & eacute; ter.The present Invention Bertalanffy has time to complete the process in the range of 14 to 22 <; em >; <; / em >; hours. These Conjugates of oligosac & nbsp; & nbsp ridoprote are na &; 'tiles in the production & amp; n of monovalent or polyvalent and as diagnostic tools & acute; s. <; / p >;<;p>;PROCESO MEJORADO DE CONJUGACIÓ;N PARA OBTENER NUEVOS CONJUGADOS SINTÉ;TICOS DE OLIGOSACÁ;RIDOS SINTÉ;TICOS- PROTEÍ;NAS (OS-PR). EL MÉ;TODO DE CONJUGACIÓ;N OS-PR SINTÉ;TICO ES UN MÉ;TODO RÁ;PIDO PARA LA OBTENCIÓ;N DE CONJUGADOS DE OLIGOSACÁ;RIDO-PROTEÍ;NA QUE SON ALTAMENTE INMUNOGÉ;NICOS Y PROVOCAN RESPUESTAS INMUNITARIAS ESPECÍ;F
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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