FRED HUTCHINSON CANCER RESEARCH CENTER;ABBVIE INC.
发明人:
ZAGER, RICHARD A.,ANDRESS, DENNIS
申请号：
EP14760019
公开号：
EP2964671A4
申请日:
2014.03.10
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
Methods are provided for treating acute kidney injury in a subject, particularly ischemia-induced kidney injury and/or hypoxia-induced kidney injury. The methods comprise administering to the subject an ETA receptor antagonist, such as atrasentan or a pharmaceutically acceptable salt thereof. Methods of diagnosing and treating such kidney injuries are also provided. Methods of reducing or preventing loss of kidney function and/or renal mass or volume, and methods of delaying progression to chronic kidney disease are also provided.
