ABBIVE INC.;FRED HUTCHINSON CANCER RESEARCH CENTER
发明人:
Richard A. Zager,Dennis Andress
申请号：
US14772621
公开号：
US20160015701A1
申请日:
2014.03.10
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Methods are provided for treating acute kidney injury in a subject, particularly ischemia-induced kidney injury and/or hypoxia-induced kidney injury. The methods comprise administering to the subject an ETA receptor antagonist, such as atrasentan or a pharmaceutically acceptable salt thereof. Methods of diagnosing and treating such kidney injuries are also provided. Methods of reducing or preventing loss of kidney function and/or renal mass or volume, and methods of delaying progression to chronic kidney disease are also provided.
