Fred Hutchinson Cancer Research Center;AbbVie Inc.
发明人:
Zager, Richard A.,Andress, Denni
申请号：
AU2014225320
公开号：
AU2014225320A1
申请日:
2014.03.10
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
Methods are provided for treating acute kidney injury in a subject, particularly ischemia-induced kidney injury and/or hypoxia-induced kidney injury. The methods comprise administering to the subject an ETA receptor antagonist, such as atrasentan or a pharmaceutically acceptable salt thereof. Methods of diagnosing and treating such kidney injuries are also provided. Methods of reducing or preventing loss of kidney function and/or renal mass or volume, and methods of delaying progression to chronic kidney disease are also provided.
