Methods and systems related to intelligent interruption handling by digital assistants are disclosed. In some embodiments, a first information provision process is initiated in response to a first speech input. The first information provision process comprises preparing a first response and a second response to the first speech input. After or concurrent with the provision of the first response to the user, but before provision of the second response to the user, an event operable to initiate a second information provision process is detected. The second information provision process is initiated in response to detecting the event. The second information provision process comprises preparing a third response to the event. A relative urgency between the second response and the third response is determined. One of the second response and the third response is provided to the user in an order based on the determined relative urgency.