Cell cultivation process

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专利权人:

Christoph E. Joosten;Christian Leist;Jörg Schmidt

发明人:

Christoph E. Joosten,Christian Leist,Jörg Schmidt

申请号：

US13643996

公开号：

US08765413B2

申请日:

2011.04.25

申请国别(地区):

US

年份:

2014

代理人:

摘要：

This invention relates to a cell culture process for the production of polypeptides in mammalian CHO cells characterized by one or more temperature and pH shifts which are adjusted in respect to their timing and step size to reduce cell death, increase product yield and improve product quality.

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中国工程科技知识中心

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http://www.ckcest.cn/home/