NOUVELLES SPIRO[3H-INDOLE-3,2´-PYRROLIDIN]-2(1H)-ONE COMPOSÉS ET LEUR DÉRIVÉS COMME INHIBITEURS DE MDM2-P53

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专利权人:

Boehringer Ingelheim International GmbH

发明人:

申请号：

EP15732007.8

公开号：

EP3164401B1

申请日:

2015.07.02

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention relates to compounds of formula (I) wherein the groups R1 to R3, R7, U, V, W, X, Y, n and q are as defined herein, their use as inhibitors of MDM2-p53 interaction, pharmaceutical compositions which contain compounds of this kind, their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases and synthetic intermediates.

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