MANUEL HENRY,JUERGEN RAMHARTER,JOACHIM BROEKER,ANNIKA GILLE,ANDREAS GOLLNER,NINA TOELLE,HARALD WEINSTABL
申请号:
PT15751029
公开号:
PT3183254T
申请日:
2015.08.20
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
The present invention encompasses compounds of formula (I) wherein the groups R1 to R7, A, V, W, X, Y, n, r and q are as defined herein, their use as inhibitors of MDM2-p53 interaction, pharmaceutical compositions which contain compounds of this kind, their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases, and synthetic intermediates.