RAMHARTER, JUERGEN,BROEKER, JOACHIM,GILLE, ANNIKA,GOLLNER, ANDREAS,HENRY, MANUEL,TOELLE, NINA,WEINSTABL, HARALD
申请号:
CA2956129
公开号:
CA2956129A1
申请日:
2015.08.20
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention encompasses compounds of formula (I) wherein the groups R1 to R7, A, V, W, X, Y, n, r and q are defined in claim 1, their use as inhibitors of MDM2-p53 interaction, pharmaceutical compositions which contain compounds of this kind, their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases, and synthetic intermediates.