RAMHARTER, Juergen,BROEKER, Joachim,GILLE, Annika,GOLLNER, Andreas,HENRY, Manuel,TOELLE, Nina,WEINSTABL, Harald
申请号:
PH12017500252
公开号:
PH12017500252A1
申请日:
2017.02.10
申请国别(地区):
PH
年份:
2017
代理人:
摘要:
The present invention encompasses compounds of formula (I) wherein the groups R1 to R7, A, V, W, X, Y, n, r and q are defined in claim 1, their use as inhibitors of MDM2-p53 interaction, pharmaceutical compositions which contain compounds of this kind, their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases, and synthetic intermediates.