human papilloma virus polypeptide, capsomer, virus-like particle, immunogen composition, nucleic acid molecule, and methods for making the polypeptide, and for preparing an immunogenic composition
BRIGITTE DESIREE ALBERT COLAU,GUY JEAN MARIE FERNAND PIERRE BAUDOUX,NAJOUA DENDOUGA,NICOLAS PIERRE FERNAND LECRENIER,SANDRA GIANNINI
申请号：
BRPI1014718
公开号：
BRPI1014718A2
申请日:
2010.06.24
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
This disclosure provides novel human papillomavirus (HPV) protein constructs and their use in the prevention of HPV disease. The constructs are chimeric proteins comprising L1 proteins with an HPV L2 peptide inserted in to the L1 protein. Such chimeric proteins may be formulated into immunogenic e.g., vaccine compositions, and optionally formulated with HPV L1 VLP based vaccines.
