PAPILLOMAVIRUS-LIKE PARTICLES (VLP) AS BROAD SPECTRUM HUMAN PAPILLOMAVIRUS (HPV) VACCINES

• 收藏
• 分享

专利权人:

发明人:

申请号：

EP10762572.5

公开号：

EP2416798B1

申请日:

2010.04.12

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

This invention relates, e.g., to a virus-like particle (VLP) composition assembled from a chimeric polypeptide comprising a papilloma virus (e.g., human papillomavirus, or HPV) L1 major capsid protein, into which is inserted a surface-displayed peptide comprising a neutralizing epitope of a papillomavirus L2 protein. Vaccine compositions comprising the VLP are described, as well as methods for inducing an immune response (e.g., vaccinating) a subject against papilloma virus, using the VLP, and kits comprising the VLP, for carrying out a method of the invention.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/