Govindappa, Nagaraj,Soares, Maria Melina,Sastry, Kedarnath
申请号:
AU2014249405
公开号:
AU2014249405A1
申请日:
2014.03.10
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present invention relates generally to the field of generating recombinant chimeric fusion proteins to be used in the cancer therapy, and more specifically, to fusion molecules of Anti- EGFRl-TGFβRII, Anti-EGFR1-PD1 and Anti-CTLA4-PD1 and methods of generating same, wherein the methods reduce production costs and increase homogeneity of the recombinant chimeric fusion proteins.