GOVINDAPPA, NAGARAJ,SOARES, MARIA MELINA,SASTRY, KEDARNATH
申请号:
EP14779937
公开号:
EP2970512A4
申请日:
2014.03.10
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention relates generally to the field of generating recombinant chimeric fusion proteins to be used in the cancer therapy, and more specifically, to fusion molecules of Anti-EGFR1-TGF&bgrRII, Anti-EGFR1-PD1 and Anti-CTLA4-PD1 and methods of generating same, wherein the methods reduce production costs and increase homogeneity of the recombinant chimeric fusion proteins.