Arico, Beatrice Maria,Brunelli, Brunella,Comanducci, Maurizio,Pizza, Mariagrazia,Savino, Silvana,Scarselli, Maria
申请号：
AU2013202606
公开号：
AU2013202606A1
申请日:
2013.04.05
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2013202606A120130502.pdf#####ABSTRACT The M01573 sequence of meningococcal fHbp offers poor coverage in a vaccine. The invention addresses this poor coverage in two ways. In a first aspect, a fHbp-based vaccine includes two family I fHbp sequences, one which is more closely related to MC58 than to M01573, and vice versa. In a 5 second aspect, a multi-family flibp-based vaccine uses a family I fHbp sequence which is more closely related to MC58 than to M01573, in combination with a family III fl-Ibp sequence.
