#$%^&*AU2014213504B220160811.pdf#####MULTIVALENT MENINGOCOCCAL DERIVATIZED POLYSACCHARIDEPROTEIN CONJUGATES AND CORRESPONDING VACCINES ABSTRACT The present invention describes derivatized polysaccharide-protein conjugates, a composition comprising one or more of such derivatized polysaccharide-protein conjugates and methods of immunizing human patients with the same. The derivatized polysaccharide-protein conjugates are purified capsular polysaccharides from Neisseria meningitidis serogroups A, C, W -135, and Y, derivatized, chemically activated and selectively attached to a carrier protein by means of a covalent chemical bond, forming polysaccharide-protein conjugates capable of eliciting longlasting immunity to a variety of N. meningitidis strains.
