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Arginase inhibitors and methods of use
专利权人:
The Trustees Of The University Of Pennsylvania;AstraZeneca UK Limited
发明人:
CHRISTIANSON, David, W.,TOMCZUK, Bruce, Edward,POTTORF, Richard, Scott,COLASANTI, Andrew, Vargha,OLSON, Gary, Lee
申请号:
DK10734002
公开号:
DK2389352T3
申请日:
2010.01.26
申请国别(地区):
DK
年份:
2019
代理人:
摘要:
The present invention is directed to arginase inhibitor compounds of formula IA or formula IB: or a pharmaceutically acceptable salt thereof, compositions containing these compounds, and methods of their use for the treatment and diagnosis of conditions characterized by upregulation of arginase, abnormally high arginase activity, or by abnormally low nitric oxide synthase activity.
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