Christianson, David W.,Tomczuk, Bruce Edward,Pottorf, Richard Scott,Colasanti, Andrew Vargha,Olson, Gary Lee
申请号:
AU2010206535
公开号:
AU2010206535B2
申请日:
2010.01.26
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present invention is directed to arginase inhibitor compounds of formula IA or formula IB: HoN,.Xi,xi H9N,.X1.,χ{ xz ^z X "x2 ^z R 1 \ R 1 K COOH COOH IA IB or a pharmaceutically acceptable salt thereof, compositions containing these compounds, and methods of their use for the treatment and diagnosis of conditions characterized by upregulation of arginase, abnormally high arginase activity, or by abnormally low nitric oxide synthase activity.