ASTRAZENECA AB;THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人:
David W. Christianson,Bruce Edward Tomczuk,Richard Scott Pottorf,Andrew Vargha Colasanti,Gary Lee Olson
申请号：
US14959765
公开号：
US10118936B2
申请日:
2015.12.04
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention is directed to arginase inhibitor compounds of formula IA or formula IB:or a pharmaceutically acceptable salt thereof, compositions containing these compounds, and methods of their use for the treatment and diagnosis of conditions characterized by upregulation of arginase, abnormally high arginase activity, or by abnormally low nitric oxide synthase activity.
