BURKS, Heather Elizabeth,DECHANTSREITER, Michael A.,HE, Guo,NUNEZ, Jill,PEUKERT, Stefan,SPRINGER, Clayton,SUN, Yingchuan,THOMSEN, Noel Marie-France,TRIA, George Scott,YU, Bing
申请号：
DK14708992
公开号：
DK2958907T3
申请日:
2014.02.12
申请国别(地区):
DK
年份:
2018
代理人:
摘要：
The present invention relates to compounds of formula I: in which n, m, X, Y 1 , R 1 , R 2 , R 3 , R 4 and R 5 are defined in the Summary of the Invention； capable of being both potent antagonists and degraders of estrogen receptors. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with aberrant estrogen receptor activity.
