YU BING,TRIA GEORGE SCOTT,THOMSEN NOEL MARIE-FRANCE
申请号：
AP2015008618
公开号：
AP2015008618A0
申请日:
2014.02.12
申请国别(地区):
AP
年份:
2015
代理人:
摘要：
The present invention relates to compounds of formula I: in which n, m, X, Y 1 , R 1 , R 2 , R 3 , R 4 and R 5 are defined in the Summary of the Invention； capable of being both potent antagonists and degraders of estrogen receptors. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with aberrant estrogen receptor activity.
