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Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders
专利权人:
发明人:
BURKS HEATHER ELIZABETH,DECHANTSREITER MICHAEL A,HE GUO,NUNEZ JILL,PEUKERT STEFAN,SPRINGER CLAYTON,SUN YINGCHUAN,THOMSEN NOEL MARIE FRANCE,TRIA GEORGE SCOTT,YU BING
申请号:
IN6804/DELNP/2015
公开号:
IN2015DN06804A
申请日:
2015.08.03
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention relates to compounds of formula I: in which n m X Y R R R R and R are defined in the Summary of the Invention capable of being both potent antagonists and degraders of estrogen receptors. The invention further provides a process for the preparation of compounds of the invention pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with aberrant estrogen receptor activity.
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