Disclosed herein is a composition for the prevention or treatment of vitiligo or vitiligo spread comprising an interferon-inducible T-cell alpha chemoattractant (ITAC) inhibitor. The composition can suppress the action of ITAC to inhibit melanocyte migration and exhibit a hypopigmentation effect.In addition, the composition prevents or treats vitiligo or metastasis of vitiligo by suppressing the action of ITAC.在本文中所揭示係一種用於白斑病(vitiligo)或白斑病擴散(vitiligo spread)之預防或治療的組成物,其包含干擾素誘導性T細胞α趨化因子(interferon-inducible T-cell alpha chemoattractant,ITAC)抑制劑。該組成物可壓制ITAC的作用,以抑制黑色素細胞(melanocyte)遷移(migration)及展現色素過少(hypopigmentation)效應。此外,該組成物藉由壓制ITAC的作用來預防或治療白斑病或白斑病轉移(metastasis)。
