The Trustees of Columbia University in the City of New York;The Regents of the University of California
发明人:
Lloyd A. Greene,James Angelastro
申请号:
US15661699
公开号:
US20180002389A1
申请日:
2017.07.27
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to methods for treating and/or preventing tumors and/or promoting apoptosis in a neoplastic cell comprising contacting the neoplastic cell with an cell-penetrating dominant-negative ATF5 (“CP-d/n-ATF5”), wherein the CP-d/n-ATF5 is capable of inhibiting ATF5 function and/or activity.