THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF
发明人:
GREENE, Lloyd, A. A,勞埃德.,ANGELASTRO, James,.格林,詹姆士‧安杰拉史壯
申请号:
HK16105534.4
公开号:
HK1217898A
申请日:
2016.05.13
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
The present invention relates to methods for treating and/or preventing tumors and/or promoting apoptosis in a neoplastic cell comprising contacting the neoplastic cell with an cell-penetrating dominant-negative ATF5 (&ldquoCP-d/n-ATF5&rdquo), wherein the CP-d/n-ATF5 is capable of inhibiting ATF5 function and/or activity.