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BICYCLIC AMIDES AS KINASE INHIBITORS
- 专利权人:
- НОВАРТИС АГ (CH)
- 发明人:
- БОЛЬД Гуидо (CH),КАПРАРО Ханс-Георг (CH),КАРАВАТТИ Джорджо (CH),ФЛЁРСХАЙМЕР Андреас (CH),ФЮРЕ Паскаль (FR),МАНЛИ Пол У. (CH),ФАУПЕЛЬ Андреа (CH),ПИССО-ЗОЛЬДЕРМАНН Кароль (FR),ЖЕССЬЕ Франсуа (FR),ШНЕЛЛ
- 申请号：
- RU2010138639/04
- 公开号：
- RU2010138639A
- 申请日:
- 2010.09.20
- 申请国别(地区):
- RU
- 年份:
- 2012
- 代理人:
- 摘要：
- 1. (3-Trifluoromethylphenyl) -amide 5- (2-aminopyrimidin-4-yloxy) -4-fluoro-2-methyl-2,3-dihydroindole-1-carboxylic acid,! (3-Trifluoromethylphenyl) -amide 5- (6-chloropyrimidin-4-yloxy) -indole-1-carboxylic acid,! (3-Trifluoromethylphenyl) -amide 5- (6-aminopyrimidin-4-yloxy) -indole-1-carboxylic acid,! (4-Methyl-3-trifluoromethylphenyl) -amide 7- (6-aminopyrimidin-4-yloxy) -2,3-dihydrobenzo [1,4] oxazine-4-carboxylic acid,! (4-Fluoro-3-trifluoromethylphenyl) -amide 7- (6-aminopyrimidin-4-yloxy) -2,3-dihydrobenzo [1,4] oxazine-4-carboxylic acid,! (3-Trifluoromethylphenyl) -amide 7- (6-aminopyrimidin-4-yloxy) -2,3-dihydrobenzo [1,4] oxazine-4-carboxylic acid,! (4-Methyl-3-trifluoromethylphenyl) -amide 7- (6-methylaminopyrimidin-4-yloxy) -2,3-dihydrobenzo [1,4] oxazine-4-carboxylic acid,! (3-Trifluoromethylphenyl) -amide 7- (6-methylaminopyrimidin-4-yloxy) -2,3-dihydrobenzo [1,4] oxazine-4-carboxylic acid,! (3-Trifluoromethylphenyl) -amide 7- (2-aminopyrimidin-4-yloxy) -2,3-dihydrobenzo [1,4] oxazine-4-carboxylic acid, or! (4-Morpholin-4-ylmethyl-3-trifluoromethylphenyl) -amide 7- (2-aminopyrimidin-4-yloxy) -2,3-dihydrobenzo [1,4] oxazine-4-carboxylic acid,! or its tautomer, or its salt. ! 2. The compound of the formula! ! where! ! denotes a group selected from! , , , , or , ! or its tautomer, or its salt. ! 3. (4-Methyl-3-trifluoromethylphenyl) -amide 6- (2-aminopyrimidin-4-yloxy) -naphthalene-1-carboxylic acid, or! (2-Trifluoromethylpyridin-4-yl) -amide 6- (2-aminopyrimidin-4-yloxy) -naphthalene-1-carboxylic acid,! or its tautomer, or its salt. ! 4. The compound of the formula! ! where! ! denotes a group selected from! , , , or , ! or its tautomer, or its salt. ! 5. (3-Trifluoromethylphenyl) -amide 6- (2-acetylaminopyrimidin-4-yloxy) -naphthalene-1-carboxylic acid,! (3-Trifluoromethylphenyl) -1. (3-Трифторметилфенил)-амид 5-(2-аминопиримидин-4-илокси)-4-фтор-2-метил-2,3-дигидроиндол-1-карбоновой кислоты, ! (3-Трифторметилфенил)-амид 5-(6-хлорпиримидин-4-илокси)-
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
