A composition and method for treatment of cancer. The composition for treating a skin disorder, comprising: a Nitrogen Mustard or an HX salt of the Nitrogen Mustard, wherein the Nitrogen Mustard or the HX salt of the Nitrogen Mustard is in a non-aqueous vehicle or carrier that does not include petrolatum or ethanol, wherein the non-aqueous vehicle or carrier that does not include petrolatum or ethanol does not include petrolatum or ethanol. The method comprises topically applying the composition of a Nitrogen Mustard or a HX salt of the Nitrogen Mustard to the affected skin, wherein the Nitrogen Mustard or the HX salt of the Nitrogen Mustard is in a non-aqueous vehicle or carrier that does not include petrolatum or ethanol, wherein the non-aqueous vehicle or carrier does not include petrolatum or ethanol.Linvention concerne une composition et une méthode de traitement du cancer. La composition de traitement dun trouble cutané comprend: un azote de la moutarde ou un sel HX dazote de la moutarde, lazote de la moutarde ou le sel HX dazote de la moutarde étant placé dans un excipient ou support non aqueux exempt de pétrolatum ou déthanol. La méthode consiste à: procéder à une application topique de la composition dun azote de la moutarde ou dun sel HX dazote de la moutarde sur la peau malade, lazote de la moutarde ou le sel HX dazote de la moutarde étant un excipient ou support non aqueux exempt de pétrolatum ou déthanol.